Viral load and neuropathology in the SIV model
نویسندگان
چکیده
منابع مشابه
Viral load and neuropathology in the SIV model.
To investigate neuropathological processes involved in HIV infection, a longitudinal analysis of central nervous system (CNS) changes was performed using the SIV-infected macaque model. Five animals were studied during the early phase and 13 during the asymptomatic and symptomatic phases. Histopathological analyses were performed on one cerebral fixed hemisphere whereas on the other frozen hemi...
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Objective(s): HTLV-I and HIV virus quantification is an important marker for assessment of virus activities. Since there is a direct relationship between the number of virus and disease progression, HTLV- I and HIV co-infection might have an influence on the development of viral associated diseases, thus, viral replication of these viruses and co-infection were evaluated. Materials and...
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OBJECTIVES Using simian models, where SIV chronic viral loads are naturally controlled in the absence of potentially neurotoxic therapies, we investigated the neuropathological events occurring during times of suppressed viraemia and when these events were initiated. DESIGN Cynomolgus macaques were infected with SIV strains that are naturally controlled to low levels of chronic viraemia. Stud...
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ژورنال
عنوان ژورنال: Journal of Neurovirology
سال: 1999
ISSN: 1355-0284,1538-2443
DOI: 10.3109/13550289909015809